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Some small studies suggest that berberine may naturally increase the bodys own production of GLP-1, which is why it earned its natural nickname

Reduction in Risk Across Fourteen Obesity-Related Cancers A large observational study presented at the American Society of Clinical Oncology (ASCO) Annual Meeting 2025, involving more than 170,000 patients with diabetes and obesity, found that GLP-1 receptor agonists were associated with a modest but statistically meaningful reduction in the incidence of 14 obesity-related cancers , with colorectal cancer demonstrating particularly favourable outcomes when compared to patients receiving DPP-4 inhibitors

Michael F Costello, National Health and Medical Research Council Centre for Research Excellence in Women's Health in Reproductive Life, Melbourne, Victoria, Australia

Cardiovascular disease in the kidney transplant recipient: epidemiology, diagnosis and management strategies

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JAMA Netw Open 5(9):e2231982e2231982 Gao X et al (2022) Efficacy and safety of semaglutide on weight loss in obese or overweight patients without diabetes: a systematic review and meta-analysis of randomized controlled trials
