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Der dreifache Wirkmechanismus unterscheidet Retatrutide grundlegend von Dual-Agonisten wie Tirzepatid und ermglicht Forschungsanstze zu Energieverbrauch und hepatischer Lipidoxidation

Orforglipron is an investigational oral, non-peptide (small-molecule) GLP-1 receptor agonist developed by Eli Lilly, originating from a Chugai discovery program

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The newer agents have been associated with weight loss of 15 to 20% of bodyweight, which approaches that seen with bariatric surgery

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