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The clinical evidence for B12 depletion on GLP-1 therapy The data is consistent, if not yet overwhelming

Combination of GLP-1 and GIP: Studies indicate superior weight loss results, with patients losing up to 20-25% of body weight , making it potentially more effective

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Interleukin-6 delays gastric emptying in humans with direct effects on glycemic control

Losing weight while preserving muscle is the foundation of a maintenance strategy that does not require extreme restriction indefinitely
