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NICE guidance does not mandate preference for daily versus weekly formulations but recommends individualising treatment choice based on patient factors including: Lifestyle and convenience : Weekly injections may suit busy schedules Tolerability : Some patients experience fewer gastrointestinal side effects with certain formulations Clinical efficacy : Specific medications may provide better glucose control or weight loss for individual patients Cost-effectiveness : NHS formularies may influence availability Your GP or diabetes specialist nurse will discuss which dosing schedule best suits your circumstances, taking into account your treatment goals and personal preferences

Eli Lilly, the makers of Zepbound, gained FDA approval for its drug orforglipron, sold under the brand name Foundayo, on April 1, 2026, following Novo Nordisk, which received approval for the Wegovy pill in December 2025

Device performance was assessed on days 1-2, 7-9, and 15-16 by comparison with a laboratory reference device

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In a statement released March 10, Novo Nordisk said it initially received inspectional observations from the FDA in February 2025, and that it has been working diligently to address those observations ever since. In the statement on Tuesday, the drugmaker acknowledged it received the warning letter and that it welcomes further dialogue with the US FDA. The company said it is working diligently to address the concerns of the FDA