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glp-1 drugs impact on energy levels Do Medications Make You Tired? Causes and Management Does GLP-1 Make You Tired?
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Int J Obes (Lond) 38(6):784793 Hoffman S, Adeli K (2021) Glucagon-like peptide (GLP)-1 regulation of lipid and lipoprotein metabolism

Blackwell Publishing

Associations of socioeconomic status and healthy lifestyle with incident early-onset and late-onset dementia: A prospective cohort study

Fralick, Zinman
Moreover, in DNA methylation alterations of tumor cells induced by GLP-1RAs, studies have demonstrated that during breast cancer progression, tumor suppressor genes such as ESR1, CDH1, and ADAM33 are downregulated due to hypermethylation alterations in their promoter regions

Therefore, both these lifestyle factors and obesity itself represent a significant risk factor for metabolic disease T2DM [3, 5]
