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Target: 75-80% of weight loss from fat, maximum 20% from muscle

1 Similarly, the active ingredient tirzepatide is marketed by Eli Lilly as two separate drugs under the brand names Mounjaro (injection for diabetes, approved in 2022) and Zepbound (injection for weight loss, approved in 2023)

Effects of semaglutide and liraglutide on urinary albumin-to-creatinine ratio (UACR) - a pooled analysis of SUSTAIN 6 and LEADER

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Cumulative weight loss at the 1.2mg dose was 8.1% at day 57, four weeks after the final dose, suggesting durable pharmacodynamic effect consistent with the observed 380 hour half-life