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It is worth noting that, as a consequence of the exceptional clinical success of GLP-1 RA drugs, and the emergence of more convenient administration routes ( e.g., oral), the demand for these drugs has risen sharply, leading to compounding and counterfeiting of marketed drug products using APIs supplied by different manufacturers

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79-LB: an open-label, active-controlled phase 2 evaluation of novel GLP-1 analog ecnoglutide in adults with obesity

The primary question emerging from the extant evidence is: why did the pronounced neuroprotective effects observed in laboratory settings and the significant risk-reduction signals in population studies not translate into a therapeutic advantage for patients with early Alzheimers disease in the EVOKE trial