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Some patients transition to lower doses or extended-interval dosing (every 1014 days instead of weekly) to maintain partial appetite suppression while reducing cost or side effects

demonstrated that GLP-1 RAs could alleviate cytoplasmic Ca 2+ overload in VSMCs in SHRs, improve the arterioles systolic and diastolic functions, and reduce BPV by upregulating Na + /Ca 2+ exchanger 1 (NCX1) expression via the Akt signaling pathway [80]

These symptoms may be related to lower food intake, dehydration, blood sugar changes, poor sleep, or the body adjusting to treatment

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[DOI] [PMC free article] [PubMed] [Google Scholar] 14.From glycemic control to gut telescoping: intussusception in a patient on a glucagon-like peptide-1 receptor agonist