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Possible neuroendocrine regulation of GLP-1 secretion is supported by studies in rodents in which nutrient flow to the distal intestine is prevented, precluding direct L-cell contact in this part of the intestine to luminal nutrients, [289,320]

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The publisher of this article is not responsible for typographical errors, manufacturer changes to the product after publication, or individual consumer outcomes

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Semaglutide represents a major advancement in GLP-1 agonist development

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Interestingly, a large meta-analysis that included data from 34,043 individuals with NAFLD, who were diagnosed either with imaging studies or histological evidence and were followed over a median period of 6.9 years, suggested that there was a 64% higher risk for experiencing both fatal and nonfatal cardiovascular events vs

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