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The concern with these medications is that the delayed gastric emptying leads to residual gastric contents, which may increase the risk of aspiration

Although data from early phase trials suggest that retatrutide is well tolerated with a similar adverse event profile to GLP-1 RAs, additional research assessing long-term safety and efficacy of retatrutide in people living with obesity and/or T2D (including cardiovascular outcomes) is awaited over the next five years

When combined with GNC's support program, we can expect the successful outcomes of GLP-1 therapy to grow as quickly as the program will." To learn more about the products featured in GNC's curated GLP-1 support program, visit gnc.com/glp-1

Choosing a regulated, clinician-led service ensures the medication is prescribed appropriately and supplied in line with MHRA standards, offering safety and continuity

The primary clinical concerns involve gastrointestinal (GI) side effects leading to dehydration, delayed gastric emptying affecting oral medication absorption, and increased aspiration risk during sedated procedures