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In HF with preserved ejection fraction and mildly reduced ejection fraction, semaglutide improved symptoms, physical function, natriuretic peptide levels, echocardiographic parameters, and HF hospitalizations, as shown in the STEP-HFpEF program and a pooled analysis of trials

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"Ozempic face" is a colloquial term describing the gaunt or hollowed appearance after significant weight loss when using GLP-1 medications.