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Abrams BF, Leonard SA, Kan P, Lyell DJ, Carmichael SL

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The answer is yes but slowly

It is important to note that these metabolic adaptations are generally physiological responses to weight loss rather than pathological changes

Combination approacheswhether through co-administration or unimolecular polypharmacologyare particularly attractive for underexplored peptides whose strengths lie in domains not fully addressed by current standards of care