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This scenario is frequently misinterpreted

In the liraglutide group ( n = 113), 51 participants (43.3%) achieved 5% BMI reduction compared to 20 participants (18.7%) in the placebo group ( n = 105), with an estimated difference of -4.64 percentage points [95% confidence interval (CI): -7.14 to -2.14] in the intention-to-treat analysis

J Clin Neurosci

Who Is a Candidate for GLP-1/GIP Weight Loss Therapy

A small retrospective study found that patients prescribed semaglutide for weight loss experienced reduced symptoms of AUD (Richards JR et al, J Clin Psych 2024;85(1):23m15068)

To sum up, GLP-1 receptor agonists protect neurons through several pathways including the classic cAMP/PKA/CREB pathway, the PI3K/Akt pathway, controlling inflammation, and keeping mitochondria working as shown in Figure 1