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Less common but serious risks include pancreatitis, gallbladder disease (including gallstones), acute kidney injury (usually secondary to dehydration), and a possible increased risk of medullary thyroid carcinoma, which has been observed in rodent studies but not confirmed in humans

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Of the GLP-1 group, 53.4% received metformin, 38.9% received glucocorticoids or mineralocorticoid, 32.5% received penicillins or a beta-lactam antibiotic, and 22.9% received non-steroidal anti-inflammatory analgesics (NSAIDs)