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The injection also has a higher and more predictable absorption in the body

Hives (urticaria) are raised, itchy welts on the skin that result from histamine release during allergic or hypersensitivity reactions

A double-blinded placebo-controlled phase 2 clinical study in obese patients weekly injections of mazdutide (9 mg) could cause 15.4% decreases in body weight over placebo after 24 weeks

Orlistat (Xenical 120mg, Alli 60mg) is licensed for adults with BMI 30 kg/m or 28 kg/m with weight-related risk factors

Other Potential Uses Semaglutide offers benefits beyond managing diabetes and weight loss

While this class of drugs can curb overeating, it may also reduce interest in pleasurable activities, potentially contributing to emotional blunting in some individuals