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For patients where cardiovascular risk reduction is the primary goal and a proven CVOT is required, liraglutide (or semaglutide) may be preferred

In 2022, global pooled analyses estimated that approximately one in eight individuals worldwide were living with obesity, encompassing 890 million adults and 160 million children and adolescents [2]

A full medical screening is required prior to starting treatment

Once researchers adjusted for other factors that could affect the risk of epilepsy, such as age, high blood pressure and cardiovascular disease, they found that people taking the GLP-1 drugs were 16% less likely to develop epilepsy than people taking the DPP-4 inhibitors

Retatrutide is an investigational triple receptor agonist targeting GLP-1, GIP, and glucagon receptors to promote weight loss and improve blood sugar control in obesity and type 2 diabetes