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This comprehensive review critically evaluates recent advances in BBRs anti-obesity pharmacology through three lenses: (1) preclinical and clinical evidence from randomized controlled trials, (2) molecular mechanisms underlying metabolic regulation, and (3) innovative strategies for pharmacokinetic optimization

ET on Nov 22, 2025

The findings are based on analysis of data from 2.4 million participants.

Understanding response variabilityinformed by biomarkers and genetic contextcan help guide conversations with healthcare providers about optimization strategies

The evidence suggests that traditional management strategies focusing on either condition in isolation fall short of addressing the intertwined nature of diabetes and depression