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Propensity score matching (PSM) with 1:1 ratio was employed to create balanced cohorts

Consider this post the context-setting for the 2026 Health Populi TrendCast which youll see next week

While glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are known to increase heart rate (HR), it is insufficiently recognized that the extent varies greatly between the various agonists and is affected by the assessment methods employed

Doctors say this side effect is legit.

Five clinical trials in type 2-diabetic subjects (SURPASS 15) have shown that tirzepatide at 515 mg per week reduces both HbA1c (1.24 to 2.58%) and body weight (5.411.7 kg) by amounts unprecedented for a single agent
