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A previous review of animal studies from the University of Amsterdam linked GLP-1 exposure during pregnancy to reduced foetal growth and skeletal abnormalities, and while human data is limited, the potential risks remain concerning

Moreover, no clinically significant impact was detected even in cases of a decrease in the AUC

Glucagon-like peptide-1, but not glucose-dependent insulinotropic peptide, inhibits glucagon secretion via somatostatin (receptor subtype 2) in the perfused rat pancreas

doi: 10.3345/cep.2022.01312, 41

The vast majority of these (over 82%) occurred in 2023 alone

The very high and constant levels of GLP-1 agonists that occur after they are injected probably explain both their beneficial effects and their side effects, for example, activation of the part of the brain that makes us feel nauseous