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doi: 10.3390/ijms26010364

Figure 2 Exenatide, a peptide of 39 amino acids, has a much slower metabolism than endogenous GLP-1 (half-life of 3-4 h) (119, 120)

Kumar S, Xu J, Perkins C, Guo F, Snapper S, Finkelman FD, et al

LAMP3 inhibits autophagy and contributes to cell death by lysosomal membrane permeabilization

Its December 5, 2017 approval as once weekly Ozempic for diabetes provided potent glycemic control and significant weight loss in a convenient weekly injection

Furthermore, this targeting principle requires additional validation, particularly in the context of human biology, before tangible conclusions regarding its applicability to clinical pharmacology can be made