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Compared to endogenous receptor ligands, retatrutide exhibits a stronger affinity for the GIP receptor than for the glucagon and GLP-1 receptors [112]

Figure 1 Statements Author contributions JC, AM, YW, CL, HQ, XM, HY, and LD searched the data, JC, XR, and JZ wrote the main manuscript text

Although addressing obesity can be challenging, all healthcare professionals should discuss a patients weight in a sensitive, nonjudgemental manner (Box 2)

24 This opens the door to exploring these novel compounds as potential therapeutic agents in a broader range of conditions
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