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This systematic review evaluates the efficacy, tolerability, and neurobiological rationale of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) and dual GLP-1/glucose-dependent insulinotropic peptide (GIP) agonists in treating nicotine use disorder (NUD), with particular attention to smoking abstinence, craving reduction, weight gain mitigation, and mechanistic insights

Prioritise your Gut for Better Results If your GLP-1 medication is not giving you the results you had hoped for, it could be helpful to take a closer look at your gut

Heightened susceptibility of females to the aversive effects of GLP1R agonists could therefore involve increased activation of these brain circuits

This trend appears to be continuing, bringing net costs even lower than presented in this report (based on data into 2024)

Twenty-nine studies were reviewed with follow-up ranging from 1 to 22 years