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Our approach: Every weight loss patient at Moonshot gets baseline DEXA scanning to track body composition over time

Table 1 Efficacy of GLP-1 agonists efficacy (adapted from UpToDate) ( GLP-1, glucagon-like peptide 1

While GLP-1 receptor expression in the liver is debated among researchers, these medications appear to influence liver health through both direct and indirect mechanisms

A few passed 17 kilograms (37 pounds) in 40 weeks

Consistency matters more than the specific day or time

Loss of function mutation of Parkin leads to exacerbation of NLRP3 activation in blood-derived macrophages via induction of A20 (Mouton-Liger et al., 2018)