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Weekly dosing to steady-state plasma levels can take about 6 to 7 weeks, so early changes may not reflect full effect

American Journal of PhysiologyRegulatory, Integrative and Comparative Physiology, 283, R99R106
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T-cells and macrophages peak weeks after experimental stroke: Spatial and temporal characteristics
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The letter did not cite manufacturing, safety, or medication quality problems
Confirm you have the right dose (see: pen label) before each injection