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Compounded versions may be more accessible, though they are not identical to the brand-name product and quality can vary between compounding pharmacies

[DOI] [PMC free article] [PubMed] [Google Scholar] 113.Vedamurthy D., Burke F., Suri K., Soffer D., Jacoby D

Studies in metabolic disease consistently report elevated systemic LPS levels associated with dysbiosis and metabolic endotoxemia (Dong et al., 2022), and these increases correlate with -cell transcriptional stress signatures observed in scRNA-seq analyses, including the expansion of ATF4 + and XBP1 + subclusters and the downregulation of maturity-related transcription factors such as PDX1 and MAFA under inflammatory conditions (Sokolowski et al., 2024)

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Tirzepatide Tirzepatide is a dual glucose-dependent insulinotropic polypeptide (GIP) and GLP-1 receptor agonist

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