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In animal models, GIP activation has been shown to reduce inflammation in adipose (fat) tissue and potentially improve how the body stores and mobilizes fat

Understanding the Risks and Making Informed Choices What We Know for Sure Research clearly shows: GLP-1 medications should not be used during pregnancy A 2-month washout period is necessary before conceiving Accidental early exposure doesnt automatically mean harm Animal studies show potential risks to developing babies Human data is limited but somewhat reassuring What We Dont Know Yet We still need more research on: Long-term effects on babies exposed during pregnancy Whether different GLP-1 drugs have different risk levels Impact on babies when used in the second and third trimesters Effects on breastfeeding and breast milk Making Your Decision Talk openly with your healthcare team about: Your weight loss goals Your pregnancy timeline Your overall health needs Your risk factors Your emotional readiness Together, you can create a plan that protects your health and your future baby

Patients who had taken GLP-1s were propensity-score matched based on age, sex, type 2 diabetes and BMI

Whole Plant Foods Naturally Support Satiety One of the biggest misconceptions about plant-based eating is that it leaves people hungry

10.1016/j.cmet.2017.11.003 [DOI] [PubMed] [Google Scholar] Wallner M, Kolesnik E, Ablasser K, Khafaga M, Wakula P, Ljubojevic S, Thon-Gutschi EM, Sourij H, Kapl M, Edmunds NJ, Kuzmiski JB, Griffith DA, Knez I, Pieske B, von Lewinski D (2015) Exenatide exerts a PKA-dependent positive inotropic effect in human atrial myocardium: GLP-1R mediated effects in human myocardium

Glucagon like peptide-1 (7-36) amide (GLP-1) nerve terminals densely innervate corticotropin-releasing hormone neurons in the hypothalamic paraventricular nucleus