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This may be attributed to the target site being located just upstream of the last five base pairs of the open reading frame at the C-terminal end of exon 14 in the Alb gene (Fig

[PubMed] 175.Das S.R., Everett B.M., Birtcher K.K., et al

Dose may be increased in increments of 2.5 mg every 4 weeks as needed
