semaglutide and type 1 diabetes Off-label semaglutide, tirzepatide lower HbA1c, weight in Health Rounds: Novo Nordisk's semaglutide
Description
Foundayo (Orforglipron) Foundayo, approved in April 2026, stands out as a daily oral pill without food or water restrictions

Semaglutide is a powerful glucagon-like peptide-1 (GLP-1) receptor agonist that suppresses appetite and blood sugar, but taking more than your prescribed dose can trigger serious side effects
The VTA may be a site mediating ghrelin effects on FAA for palatable food access, as intra-VTA ghrelin administration in rats entrained with access to a palatable high fat diet increases consumption in a GHSR dependent manner [56]

The non-GLP-1 alternatives matter for patients who cannot tolerate GLP-1s or do not meet eligibility, a unique hedge

Grocery shopping changes

Taking three deep breaths before injecting and consciously relaxing my muscles makes a noticeable difference
