is semaglutide the same as glp 1 GLP-1 Ozempic? Structure of semaglutide (subcutaneous formulation)

And while brain research into GLP-1 and reward circuits is still in its early days, its a field to watch closely

[DOI] [PubMed] [Google Scholar] 52.Thomas JG, Raynor HA, Bond DS, Luke AK, Cardoso CC, Foster GD, Wing RR

A systematic review of over 94,000 adults seeking obesity treatment found that 14% had binge eating disorder on clinical interview and up to 26% reported moderate-to-severe binge eating on self-report measures ( Melville et al., Int J Eating Disorders, 2025 )

Image source: GLP-1s and Food Noise One of the interesting impacts of the GLP1 medications is the reduction of what is called food noise, also known as food-related intrusive thoughts or food preoccupation (Mozafariun 2025)

Additional studies will be required to determine whether metformin can increase incretin receptor expression in human beta cells and thereby bolster incretin action in a meaningful way

GLP-1 medications are large molecules, about seven times bigger than what your skin can naturally absorb