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Should patients with osteoarthritis ask about GLP-1 therapy

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AWARD-7 enrolled adult patients with T2D (A1c, 7.5%10.5%) and CKD stages 34 who were being treated with ACEi or ARBs and found that dulaglutide (0.75 or 1.5 mg subcutaneous once weekly) achieved similar glycemic control to insulin glargine but had significantly less eGFR decline (mean 0.7 vs 3.3 mL/min/1.73 m 2 , respectively

Western Blot Analysis Cells were lysed with 1X Laemmli sample buffer (BioRad, 1610737), boiled at 95 C for 5 min, and centrifuged at 14000 g for 15 min at 4 C to remove the undissolved cell debris

Because tirzepatide works gradually, stopping temporarily may affect appetite regulation and blood sugar stability

Specifically, the FDA has not approved Ozempic for weight loss, but those with Type 2 Diabetes that use this drug, tend to slim down