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Description
These studies indicate that GLP-1 modulates the release of several neurotransmitters including serotonin, dopamine, GABA, and glutamate, which may regulate depressive-like behaviors

Heart failure, saxagliptin, and diabetes mellitus: observations from the SAVOR-TIMI 53 randomized trial

Patients taking tirzepatide with insulin or sulfonylureas should be especially cautious and may need medication dose adjustments when consuming alcohol
Note: This study is about Zepbound (tirzepatide), not Foundayo (orforglipron)
This often happens if key lifestyle factors begin to drift or become irregular without necessary structure constantly

J Card Fail 2025;31:66-1164
