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The heterogeneity of NEN presentation caused by diverse primary sites, a spectrum of behavior ranging from indolent to aggressive, and functional statuses complicates treatment optimization [8]

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Keeping GLP-1's off-plan avoids the challenge of manufacturer dictated limits on prior authorizations and step therapy - a true danger point for plans wanting the benefits of these drugs with appropriate guard rails to ensure they are used appropriately

Higher risk factors include older age, being male, advanced diabetes, existing eye disease, and cardiovascular disease

Tolerability only

The bioavailability (how much drug reaches your bloodstream) may differ between delivery methods