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* Monitor Other Hemodynamic and Biochemical Parameters: BP, HR, Lipid Profile, creatinine, General Urine Test with Urinary Albumin-to-Creatinine ratio (UACaR)

Males faced a higher prevalence of leukemia and urinary cancers, while females had increased thyroid and throat cancers

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To prove the superiority of the combination therapies, clinical trials were designed to test whether the combination has a superior efficacy over monotherapy

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