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Emerging evidence suggests these agents also exert direct dermatologic effects

Emerging brands like Replenza, Keptropy, and FullWell are marketing GLP-1-supportive supplements via direct-to-consumer channels, with emphasis on glycemic control, lean mass preservation, and post-meal tolerance

The safety and glycaemic efficacy of tirzepatide as an additional treatment for Japanese subjects with T2D who were not achieving adequate glycemic control with various oral antihyperglycaemic monotherapies (SURPASS-J combo trial) were similar to those observed in the SURPASS-J mono trial [141]

Treatment decisions, including dosing, should be guided by a licensed provider based on clinical considerations

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Genetic and Biased Agonist-Mediated Reductions in -Arrestin Recruitment Prolong cAMP Signaling at Glucagon Family Receptors