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That's a genuinely significant development in obesity medicine, and it's the reason GLP-1 therapy has moved from "cosmetic weight loss medication" to "cardiometabolic treatment" in clinical guidelines
NICE guidance provides medicine-specific criteria: Orlistat : A lipase inhibitor that reduces fat absorption
The risk factors for developing anthracycline-induced cardiotoxicity are cumulative anthracycline dose, advanced age, pretreatment low-normal LVEF, prior cardiovascular disease, as well as other established cardiovascular risk factors (e.g., hypertension, diabetes, obesity, smoking)
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