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Some patients also notice an upset stomach, nausea, constipation, diarrhea, or a heavy, full feeling, especially at the beginning or with higher doses

Research is mixed, but a 2025 systematic review reported that microbiome interventions (e.g., probiotics) generally improved body weight, body fat percentage, and metabolic parameters (e.g., lipid levels, glucose metabolism) in people with obesity

South Carolinas obesity rate is worse than its northern neighbors, at 36% of all adults, according to 2023 data from the CDC, the most recent available

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S., El-Sheakh, A