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These findings increase the clinical relevance of liver endpoints in obesity pharmacotherapy, while also underscoring the limits of direct cross-trial comparison across differences in disease stage, endpoint definition and trial design Weight regain after treatment discontinuation deserves particular emphasis

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Ideally at least 4-5 litres of clear fluid should be drunk from 24 hours before your colonoscopy until 6 hours before your colonoscopy (when drinking should cease)

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