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According to a This review also reports that it may be more effective for people to take creatine supplements pre- and post-workout to increase creatine stores, muscle mass, and strength gains

A network meta-analysis comparing multiple weight loss approaches found semaglutide achieves 13.7% average weight loss compared to phentermine combined with topiramate at 9.1%
SGLT-2 Inhibitors: The Gap Seems to Be Leveling Off

Duration of therapy also matters

Studies show that despite initial weight reduction, patients with PWS inevitably experience weight regain and long-term efficacy is questionable (5456)

Appl Health Econ Health Policy 2010;8(4):267280
