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Pharmacological inhibition of the NLRP3 inflammasome suppressed PFKFB3-driven glycolysis and vice versa, resulting in decreased lactate production in TGF-1+IL-1-stimulated lung fibroblasts
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Repatha is used to lower high cholesterol alongside dietary changes and to reduce the risk of major cardiovascular events in those at increased risk for these events, such as death from cardiovascular disease, heart attack, stroke, angina requiring hospitalization, or certain types of heart surgery

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