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Completers on liraglutide 2.4/3.0mg (n=92) maintained a 2-year weight loss of 7.8kg from screening

Changes in the expression of GLP-1R, Iba-1, PI3K and p-Akt in the TNC were examined by western blotting

A new randomized clinical trial just published inJAMA Psychiatrytested semaglutide (a GLP-1 agonist) in people with schizophrenia, prediabetes, and obesity who were taking antipsychotics

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Pfizers dose-optimization studies of once-daily formulations of danuglipron ( NCT06567327 and NCT06568731 ) met key pharmacokinetic objectives and confirmed a formulation and dose with the potential to deliver a competitive efficacy and tolerability profile in Phase 3 testing, based on earlier studies of twice-daily danuglipron

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