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Diabetologia 60(8):13851389

Comparison Matrix: Ozempic vs Wegovy vs Mounjaro Source: Polaris Market Research Analysis By Application Analysis Which GLP-1 Application Holds the Largest Share

Ware, J

The action of GLP-1(7-36) on cells may be more indirect, such as through the influence on hormones secreted by and cells (insulin and glucagon), which indirectly affects cell somatostatin secretion

Deamidation: Asparagine and glutamine residues undergo deamidation, creating acidic variants that alter stability and pharmacokinetics

The late stage or chronic effects can operate through modulation of gene expression and cellular metabolism [68]