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Some patients carry genetic traits that make their GLP-1 receptors more or less responsive, which can affect both hunger suppression and nausea sensitivity

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Cardiovascular Function: DPP-4 is present on the endothelial cells [5], [9]

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[1] [4] If you need to change your weekly dosing day after starting treatment, you may do so as long as your last dose was administered at least 72 hours (3 days) prior to the new dosing day

Secondary endpoints included pharmacokinetic parameters and preliminary pharmacodynamic effects