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doi: 10.1016/S0140-6736(23)01200-X

do not use if you have a history of severe gastrointestinal disease Signs of low blood sugar, for example: Dizziness, weakness, shakiness, jitteriness, headache, anxiety/mood changes, rapid heartbeat, confusion, slurred speech, sweating, or lightheadedness

Zepbound (tirzepatide for weight management) carries a warning about suicidal thoughts and behaviors

doi: 10.1001/jama.2022.0078 [DOI] [PMC free article] [PubMed] [Google Scholar] 78

Average age ~ 45 years | ~ 65% women | ~ 57% had prediabetes at randomization Average body weight ~ 113 kg | ~ 69% had a BMI 35 kg/m 2 What were the treatment conditions

Tirzepatide can cause modest increases in heart rate (average 2-4 beats per minute)