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Description
Approvals later followed for semaglutide and tirzepatide, which are sold under brand names such as Wegovy

This culminates in the development of microvascular (i.e., neuropathy, nephropathy, retinopathy) and macrovascular (i.e., myocardial infarction, peripheral vascular disease, stroke) complications [35]

Semaglutide binds to blood proteins and pools in subcutaneous tissue, so the effective pace at which it leaves you depends on how fast it moves out of those reservoirs, not just the single-number half-life printed on a label

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People with bipolar disorder, past mania, significant anxiety, substance use concerns, or alcohol-use changes should make sure those issues are part of the clinical review
