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A diverse pipeline of potential therapies for DKD exists, including incretin agonists, endothelin receptor antagonists, aldosterone synthase inhibitors, soluble guanylate cyclase stimulators and agents that target inflammatory pathways such as Janus kinase/Janus kinase 2 inhibitors and IL-6 monoclonal antibodies

The US Food and Drug Administration (FDA) has actively monitored reports of suicidal ideation associated with GLP-1 receptor agonists and dual GIP/GLP-1 receptor agonists

Several features, including NSAIDs and insulin usage, were ultimately not included in the final models

PlexusDx serves all 50 states, requires no insurance, and accepts HSA/FSA

Revita is investigational and available only through clinical trials

It simultaneously reduces production of 1-methylnicotinamide (1-MNA) from nicotinamide increasing nicotinamide availability as a NAD+ precursor