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doi: 10.1056/NEJMoa2028395 131 BolandMLLakerRCMatherKNawrockiAOldhamSBolandBBet al

Additional research is needed to better understand the long-term health outcomes, ideal patient selection and the full scope of risks and benefits for people with T1D who use these medications

As a result, further investigation is required to determine whether the variations among DPP4is could impact the occurrence of particular adverse effects

The manufacturer list price is $997.58 per month for any dose (3mg, 7mg, or 14mg), and retail pharmacy prices can reach $1,100-$1,200 after markups

doi:10.1016/j.molmet.2021.101181 64

For chemical synthesis, innovation is focused on reducing solvent volumes, finding greener reagent alternatives, and redesigning the process to be less wasteful (e.g, flow chemistry, microwave-assisted SPPS)