tirzepatide endometriosis for Endometriosis: A Practical Explanation GLP-1 in Endometriosis: What We

Lauffer LM, Iakoubov R, Brubaker PL

Key takeaways Compounded semaglutide is a customized Type 2 diabetes and weight-loss medication that may not have the same safety and efficacy as FDA-approved brands like Wegovy and Ozempic

Conclusions GI AEs were more common with semaglutide 2.4 mg than placebo, but typically mildtomoderate and transient

Maintaining balanced nutrition, hydration , regular physical activity and ongoing follow-up care may help reduce the risk of nutritional deficiencies, muscle loss and gradual weight gain while supporting safer and more sustainable long-term progress

Instead of the trees, we want to have the forest

Multiple safety and research bodies have weighed in: World Health Organization (WHO) : In June 2025, WHO issued a medical product alert highlighting NAION as a potential risk associated with semaglutide (Ozempic, Rybelsus, Wegovy)