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At the level used in this study it is not expected that long term consumption might induce a cumulative toxic effect on kidney or liver associated with the anti-nutrient compounds that are originally present in the leaves, such as saponins, tannins, terpenes or alkaloids [36]

A key role for transmembrane prolines in calcitonin receptor-like receptor agonist binding and signalling: implications for family B G-protein-coupled receptors