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Identification of extremely reactive gamma-ketoaldehydes (isolevuglandins) as products of the isoprostane pathway and characterization of their lysyl protein adducts

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On the other hand, insulin secretion was primarily stimulated by high glucose and amplificated by Gs-coupled receptors such ss GLP-1-stimulated GLP-1 receptor in GLP-1R-MIN-6 cells

Sthle M, Hellberg S, Virta J, Liljenbck H, Metsl O, Li XG, Jauhiainen M, Saukko P, Yl-Herttuala S, Nuutila P

And, based on the data so far, a significantly larger effect size than anything that came before

Thirteen studies were performed in the United States [11, 1517, 20, 22, 35, 36, 40, 4346], 9 in Denmark [12, 13, 18, 19, 21, 24, 28, 31, 34], 4 both in China [23, 33, 48, 49] and Slovenia [2527, 39], 3 in Canada [14, 29, 47], 2 in Italy [37, 38], 1 in United Kingdom [30], Sweden [32], Australia [41], and Netherlands [42], respectively