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These medications exert (in)direct hepatic actions by reducing steatosis, attenuating inflammation, and potentially reversing fibrosis, while simultaneously addressing systemic metabolic abnormalities including excessive obesity, insulin resistance, and cardiovascular risk

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Most adverse events with semaglutide treatment were mild or moderate

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Results Once-a-month single-dose semaglutide microcapsule was developed, which effectively suppressed the initial burst release down to 10%, maintained therapeutic plasma drug concentration for a month, and improved the surface appearance of microcapsules

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